WRN inhibitor 4 - Search Results

About 4 results found for searched term "WRN inhibitor 4" (0.148 seconds)

Cat.No.	Name	Target
M42913	WRN inhibitor 4	DNA/RNA Synthesis
	WRN inhibitor 4, a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor.
M11056	NSC 617145	DNA/RNA Synthesis
	NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor,IC50 The value is 230 nM. NSC 617145 inhibit WRN ATPase and induce double-strand rupture (DSB) and chromosomal abnormalities. NSC 617145 is selective to WRN and superior to BLM, FANCJ, ChlR1, RecQ, and UvrD helicases.
M30527	NCGC00029283	DNA/RNA Synthesis
	NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC50s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively.
M49841	Werner syndrome RecQ helicase-IN-4	DNA/RNA Synthesis
	Werner syndrome RecQ helicase-IN-4 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC50 value of 0.06 µM. Werner syndrome RecQ helicase-IN-4 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-4 shows anticancer activity.